Indianapolis Colts at New England Patriots (Frankfurt – NFL International Series at 9:30 AM)

The Indianapolis Colts (4-5) head to Frankfurt to take on the New England Patriots (2-7) and Bill Belichick. Gardner Minshew will start at quarterback for the Colts with rookie phenom Anthony Richardson on IR. Minshew has thrown for 8 touchdowns to 5 interceptions with a quarterback rating of 85.5. The Patriots’ third-year quarterback Mac Jones looks to turn his season around. Jones has thrown 10 touchdowns to 9 interceptions this year with a quarterback rating of 80.2. He has also lost 2 fumbles and has been sacked 16 times so far. Can Belichick and the Patriots get their third win of the season? Or will the Colts find their way back to .500 with a victory in Frankfurt?

Indianapolis Colts (-1.5) @ New England Patriots (+1.5)  – O/U 43.5

Head Referee: Tra Blake

Notable Injuries:

Colts – WR Josh Downs (Questionable), WR Alec Pierce (Questionable), LB Zaire Franklin (Questionable), CB Julius Brents (OUT)

Patriots – WR DeVante Parker (OUT), CB J.C. Jackson (OUT), CB Jack Jones (Questionable, but will likely not play), WR Demario Douglas (Questionable)

Green Bay Packers at Pittsburgh Steelers (1:00 PM)

Matt LaFleur and the Green Bay Packers (3-5) march into Acrisure Stadium in a contest with the Pittsburgh Steelers (5-3) and veteran head coach Mike Tomlin. The Green Bay Packers are coming off of a convincing win against the Los Angeles Rams. The Packers crushed the Rams 20-3, with Jordan Love throwing for 228 yards and a touchdown. The Steelers are also coming off of a nail-biting win against the Tennessee Titans from Thursday Night Football last week. Steelers’ quarterback Kenny Pickett had a mediocre game, throwing for 160 yards and a touchdown to Diontae Johnson. While the Packers look to claw their way back into the wild card race, Pittsburgh is hoping a win over Green Bay can bring them closer to a division title in the competitive AFC North. 

Green Bay Packers (+3) @ Pittsburgh Steelers (-3) – O/U 38.5

Head Referee: Scott Novak

Notable Injuries: 

Packers: LB Quay Walker (Doubtful), OL Jon Runyan (Questionable), S Rudy Ford (Questionable), DL Kenny Clark (Questionable), CB Jaire Alexander (Doubtful)

Steelers: S Minkah Fitzpatrick (OUT), DT Montravius Adams (OUT)

New Orleans Saints @ Minnesota Vikings (1:00 PM)

The New Orleans Saints (5-4) are heading to U.S. Bank Stadium to face the Minnesota Vikings (5-4) and their new quarterback, Josh Dobbs. The Saints are in some trouble, with former All-Pro receiver Michael Thomas being arrested in an off-the-field incident. Thomas is expected to play against Minnesota, however. New Orleans is coming off a close victory against Tyson Bagent and the Chicago Bears. Their Swiss army knife, Taysom Hill, threw a touchdown and caught a touchdown while also running for 52 yards. Derek Carr will still start at quarterback for the Saints. The Vikings are coming off of a comeback win against the Atlanta Falcons. After rookie quarterback Jaren Hall left the game due to a concussion, Josh Dobbs entered the game and scored three touchdowns. 2 of them came in the air while the other was scored on the ground. The Vikings look to extend their winning streak to 5 games while the Saints look to extend their division lead in the NFC South.

New Orleans Saints (-3) @ Minnesota Vikings (+3) – O/U 40.5

Head Referee: Adrian Hill

Notable Injuries:

Saints: RB Kendre Miller (OUT), DE Isaiah Foskey (OUT)

Vikings: WR K.J. Osborn (Questionable), DL Dean Lowry (Doubtful), TE T.J. Hockenson (Questionable), QB Jaren Hall (OUT)

Houston Texans at Cincinnati Bengals (1:00 PM)

Rookie quarterback C.J. Stroud and the Houston Texans (4-4) are headed into Cincinnati to face the Bengals (5-3) and their All-Pro quarterback Joe Burrow. Houston is coming into Week 10 on a high note after beating the Tampa Bay Buccaneers 39-37 in a high-scoring affair. Stroud threw for 470 passing yards and 5 touchdowns (147.8 quarterback rating) during the contest. His mark of 470 yards set a new NFL record for the most passing yards by a rookie in a single game. Meanwhile, the Cincinnati Bengals registered a 24-18 win over the Buffalo Bills on Sunday Night Football last week. Like Stroud, Joe Burrow had an exceptional outing, throwing for 348 yards and 2 touchdowns (108.9 quarterback rating) during the primetime game. Will the Bengals extend their winning streak to 5 games? Or will the Texans find their way over the .500 mark?

Houston Texans (+6.5) @ Cincinnati Bengals (-6.5) – O/U 47

Head Referee: Carl Cheffers

Notable Injuries:

Texans: WR Nico Collins (OUT), S Jimmie Ward (OUT), LB Henry To’oTo’o, RB Dameon Pierce (OUT), FB Andrew Beck (OUT), K Ka’imi Fairbairn (OUT), TE Brevin Jordan (OUT), WR Robert Woods (Questionable), DE Jerry Hughes (Questionable), CB Steven Nelson (Questionable)

Bengals: WR Tee Higgins (OUT), WR Ja’Marr Chase (Questionable), DT Josh Tupou (Doubtful), DE Sam Hubbard (OUT)

Cleveland Browns at Baltimore Ravens (1:00 PM)

The Cleveland Browns (5-3) and their veteran quarterback Deshaun Watson will enter M&T Bank Stadium to face the potent Baltimore Ravens (7-2) and their dual-threat quarterback, Lamar Jackson. Cleveland is coming off a convincing victory of 27-0 against the Arizona Cardinals in Week 9. Deshaun Watson threw for 219 yards and 2 touchdowns (107.5 quarterback rating) last week. On the flip side, the Ravens just keep winning. They crushed the then 5-2 Seattle Seahawks 37-3. Running back Gus Edwards continued his touchdown tear, adding another 2 during the contest. This divisional matchup has substantial implications for the standings in the AFC North for both the Browns and the Ravens. Who will come out victorious?

Cleveland Browns (+6.5) @ Baltimore Ravens (-6.5) – O/U 38.5

Head Referee: Land Clark

Notable Injuries:

Browns: DE Isaiah Thomas (Doubtful), RB Pierre Strong (Questionable), OT Ty Nsekhe (OUT), CB Greg Newsome (Questionable), OT Dawand Jones (OUT), WR Marquise Goodwin (OUT), WR David Bell (OUT)

Ravens: OT Morgan Moses (Questionable), RB Keaton Mitchell (Questionable), CB Marlon Humphrey (Questionable), CB Jalyn Armour-Davis (Questionable)

Tennessee Titans at Tampa Bay Buccaneers (1:00 PM) 

The Tennessee Titans (3-5) and their rookie quarterback Will Levis are heading to Tampa Bay to face the Buccaneers (3-5) and journeyman quarterback Baker Mayfield. Levis and the Titans are coming off of a disappointing loss to the Pittsburgh Steelers. The young QB is averaging 250 yards per game with 4 touchdowns and only one interception through his first 2 starts. However, after a 3-1 start, the Buccaneers are currently on a 4 game losing streak. They were unable to outduel the Houston Texans’ potent passing attack and took a heartbreaking loss. With Will Levis facing one of the worst passing defences in the NFL, can he carry the Titans to a Week 10 win? Or will Baker Mayfield and the Bucs get back into contention in the NFC South?

Tennessee Titans (+1) @ Tampa Bay Buccaneers (-1) – O/U 38.5

Head Referee: Alan Eck

Notable Injuries:

Titans: QB Ryan Tannehill (Questionable), CB Sean Murphy-Bunting (OUT), OL Nicholas Petit-Frere (OUT), CB Tay Gowan (Questionable), WR Treylon Burks (OUT), OL Daniel Brunskill (OUT)

Buccaneers: WR Trey Palmer (Questionable), DL Calijah Kancey (Questionable), DB Josh Hayes (OUT), DL Logan Hall (Questionable), OL Matt Feiler (Doubtful), OL Silas Dzansi (OUT), CB Jamel Dean (Questionable), CB Carlton Davis (Questionable)

San Francisco 49ers at Jacksonville Jaguars (1:00 PM)

Brock Purdy and the San Francisco 49ers (5-3) are entering EverBank Stadium in Jacksonville to play the Jaguars (6-2) and their quarterback, Trevor Lawrence. The 49ers are coming off of their bye week and currently possess a three game losing streak. Jacksonville also had a bye week, but they have won 5 straight games and are arguably the “team to beat” in the AFC. With two powerhouses clashing, both rosters will be tested to see where they stand amongst the best teams in the NFL. 

San Francisco 49ers (-1) @ Jacksonville Jaguars (+1) – O/U 45.5

Head Referee: Brad Allen

Notable Injuries:

49ers: OT Trent Williams (Questionable), DL Drake Jackson (OUT), DL Javon Hargrave (Questionable), LB Demetrius Flannigan-Fowles (Questionable), OL Aaron Banks (OUT)

Jaguars: S Daniel Thomas (Questionable), WR Zay Jones (OUT), OL Ezra Cleveland (Questionable), S Andre Cisco (Questionable), CB Tyson Campbell (Questionable)

Detroit Lions at Los Angeles Chargers (4:05 PM)

The Detroit Lions (6-2) are considered one of the “Top Dogs” in the NFC as they enter SoFi Stadium to face the Los Angeles Chargers (4-4) and their young QB Justin Herbert. Jared Goff and the Lions are coming off of a much-needed bye week. Goff has thrown for 12 touchdowns and 5 interceptions (96.4 quarterback rating) this season. The Chargers are coming off of a notable victory over the New York Jets 27-6. Herbert was held in check by the Jets’ secondary, but Austin Ekeler had a fantastic game where he scored 2 touchdowns. Can the Chargers’ passing defence improve and cool off a hot Detroit Lions team? Or will the Lions continue cementing themselves as a top team in the NFL?

Detroit Lions (-3) @ Los Angeles Chargers (+3) – O/U 48.5

Head Referee: Shawn Smith

Notable Injuries:

Lions: OG Halapoulivaati Vaitai, DL Levi Onwuzurike (Doubtful), OT Dan Skipper (Questionable), WR Donovan Peoples-Jones (Questionable)

Chargers: WR Joshua Palmer (IR – Knee)

Atlanta Falcons at Arizona Cardinals (4:05 PM)

The Atlanta Falcons (4-5) and their quarterback Taylor Heinicke are heading into Glendale to face the Arizona Cardinals (1-8). Former first round pick Kyler Murray will play after being sidelined for nearly 11 months due to an ACL injury. Arizona is currently on a 6 game losing streak after the loss to the Cleveland Browns last week. Atlanta fell under the .500 mark after their loss to the Minnesota Vikings in Week 9. Will Kyler Murray lead the Arizona Cardinals to their second victory of the season? Or will Taylor Heinicke and the Falcons find their way back to .500?

Atlanta Falcons (-1.5) @ Arizona Cardinals (+1.5) – O/U 43.5

Head Referee: Craig Wrolstad

Notable Injuries: 

Falcons: WR Mack Hollins (OUT), OL Barry Wesley (OUT), DL David Onyemata (Questionable), TE Parker Hesse (OUT), CB Dee Alford (OUT)

Cardinals: WR Michael Wilson (Questionable), LB Ezekiel Turner (Questionable), TE Geoff Swaim (Questionable), OL Carter O’Donnell, OL D.J. Humphries (Questionable), OL Hayden Howerton (OUT), OL Will Hernandez (Questionable), OL Trystan Colon (OUT), RB Emari Demercado (OUT)

Washington Commanders at Seattle Seahawks (4:25 PM)

Second-year quarterback Sam Howell and the Washington Commanders (4-5) are heading into Lumen Field to play the Seattle Seahawks (5-3) and 72-year-old head coach Pete Carroll. The Commanders are coming off of a 20-17 victory over the New England Patriots. Sam Howell threw for 325 yards in that game, registering a passing touchdown and an interception. The Seattle Seahawks, however, are coming off of a blowout loss to the Baltimore Ravens. Geno Smith has had a rough season thus far, throwing 9 touchdowns and a sizable 7 interceptions (86.4 quarterback rating). Can the Seattle Seahawks rebound with a win over the Commanders? Or will the Washington Commanders claw their way back to .500 with a victory over one of the NFC’s best squads?

Washington Commanders (+5.5) @ Seattle Seahawks (-5.5) – O/U 44.5

Head Referee: Alex Kemp

Notable Injuries:

Commanders: WR Curtis Samuel (Questionable)

Seahawks: TE Colby Parkinson (Questionable), RB DeeJay Dallas (Questionable), OG Anthony Bradford (OUT)

New York Giants at Dallas Cowboys (4:25 PM)

The injury-plagued New York Giants (2-7) will enter AT&T Stadium to face the Dallas Cowboys (5-3) and star pass-rusher Micah Parsons. With a season-ending injury to starting quarterback Daniel Jones, the Giants will start Tommy DeVito against one of the best passing defences in the NFL. The Giants were routed by the Raiders 30-6 in Week 9. Meanwhile, the Dallas Cowboys are coming off of a heartbreaking loss to the Philadelphia Eagles 28-23. Dak Prescott had an excellent game, throwing for 374 yards and 3 touchdowns. In a rivalry game between two historic franchises, the result is unpredictable. Can the New York Giants pull out the miracle upset against the Cowboys?

New York Giants (+17.5) @ Dallas Cowboys (-17.5) – O/U 39.5

Head Referee: Brad Rogers

Notable Injuries:

Giants: QB Daniel Jones (IR – Out For Season), TE Darren Waller (IR), OT Evan Neal (OUT), RB Deon Jackson (OUT), CB Adoree’ Jackson (OUT), OG Mark Glowinski (Questionable), RB Jashaun Corbin (Questionable), WR Parris Campbell (Questionable)

Cowboys: WR KeVontae Turpin (Questionable), LB Leighton Vander Esch (IR – Neck)

New York Jets at Las Vegas Raiders (8:20 PM)

The New York Jets (4-4) and quarterback Zach Wilson are heading into Sin City to play the Las Vegas Raiders (4-5) and rookie quarterback Aidan O’Connell. The New York Jets were crushed by the Charges last week on Sunday Night Football. They are now .500 on the year. On the flip side, the Raiders are feeling great. They fired struggling head coach Josh McDaniels and blew out the New York Giants during Week 9. They are now only 1 win away from being at the .500 mark. Will the New York Jets seal the win and play their way back into the playoff race? Or will the “Brand New Raiders” get back to .500?

New York Jets (-1) @ Las Vegas Raiders (+1) – O/U 36.5

Head Referee: Shawn Hochuli

Notable Injuries:

Jets: OT Billy Turner (OUT), LB Chazz Surratt (OUT), DL Will McDonald (Questionable)

Raiders: OT Kolton Miller (Doubtful), FB Jakob Johnson (Questionable)

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*Note: All Betting Odds mentioned throughout the article are via FanDuel Sportsbook

*Note: All times mentioned throughout the article are in Eastern Standard Time

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By Jack MacNeil

Lions, Blue Jays, Raptors. Oh the agony. “You miss 100% of the shots you don’t take.” – Wayne Gretzky – Michael Scott – Jack MacNeil.